Stella had diabetes since she was 25 years of age. When she turned 43, still suffering from diabetes, she developed diabetic neuropathy and the kind of excruciating pain that she felt due to this peripheral neuropathy was hard for her to define. She was unable to do her household work as her feet and hands use to become numb at odd hours especially at night and she used to feel an agonizing pain and burning sensation in the limbs. It was hard for her to, even sleep at night due to this throbbing pain. That is when her friend suggested her to use Lyrica. She used Lyrica and within few weeks of treatment with Lyrica, she was back to her normal life living it to the fullest. Neuropathic pain is a dreaded condition characterized by complex chronic pain accompanied by tissue injury surrounding the peripheral nerves. Damaged peripheral nerves sends altered pain signals to the brain. Apart from diabetes, other conditions, which lead to neuropathic pain, are brain and spinal cord injury, shingles (post herpetic neuralgia) and fibromyalgia.

 

Lyrica treats neuropathic pain associated with diabetes, herpetic infection and fibromyalgia. Apart from treating neuropathic pain, Lyrica finds its use in treating partial-onset seizures. Lyrica contains Pregabalin as the main active moiety. Pregabalin acts by binding to the calcium channels of the nerves and reduces the communication between nerves and hence the ability to send pain sensation to the brain.

 

Lyrica 150 mg


Dosing regimen: The commercially available dosages of Lyrica are 50mg, 75mg and 150mg accessible in a capsule dosage form.

 

Dose for treating diabetic neuropathy: For treating diabetic neuropathy, take 50 mg of Lyrica orally, three times a day with an ample amount of water. Gradually increase the dose to 100mg, taken three times a day. Do not exceed more than 300mg/day.

 

Dose for treating postherpetic neuralgia: For treating post-herpetic neuralgia, take 75-150mg of Lyrica two times a day or 50-100mg, three times a day orally with plenty of water.

 

Dose for treating fibromyalgia: For treating fibromyalgia take 75 mg orally, two times a day initially and increase the dose to 150 mg two times a day based on efficacy and tolerability.

 

Dose for treating pain associated with spinal cord injury: For treating fibromyalgia take 75 mg two times a day initially.  The dose may be increased to 150 mg two times a day (300 mg/day) within 1 week based on efficacy and tolerability.

 

Adverse effects: The commonly seen adverse effects of Lyrica are blurred vision, dizziness, constipation, fatigue, headache and weight gain.

 

Warnings and precautions:

 

Do not use Lyrica if you are allergic to Pregabalin or any other constituent present in this medicine. Do not stop taking Lyrica suddenly as it may exhibit withdrawal symptoms. Do not drive or operate heavy equipment after using Lyrica. Do not consume alcohol or other sedatives along with Lyrica. In the presence of any hepatic, renal or cardiovascular disorder, do not take Lyrica.

 

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